BDBM375960 US10947243, Example 35::US9914735, Example 35

SMILES C[C@@H](Oc1cc(cc2nn(C)cc12)-c1csc(n1)C(F)F)[C@H]1CNC(=O)C1

InChI Key InChIKey=HBEWFEPXRNHJJQ-MWLCHTKSSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 375960   

TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375960(US10947243, Example 35 | US9914735, Example 35)
Affinity DataIC50:  34.5nMAssay Description:Recombinant human Syk (amino acids 342-635) was expressed as a fusion protein with an N-terminal GST tag, affinity-purified and deep-frozen at a conc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase SYK [342-635](Homo sapiens (Human))
Boehringer Ingelheim International

US Patent
LigandPNGBDBM375960(US10947243, Example 35 | US9914735, Example 35)
Affinity DataIC50:  1nMAssay Description:Human GSK3beta (expressed and prified from SF21 cells) is obtained from the University Dundee/Scotland (Dr. James Hastie??Dept. of Biochemistry) in 5...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent